IF1-Intrinsic Factor

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IF1-Intrinsic Factor

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Product Details

What is pernicious anaemia? Intrinsic Factor is primarily used in the diagnosis of pernicious anaemia, a condition caused by a vitamin B12 deficiency. Prevalence in the general population varies from around 3% - 5%, and increases dramatically to 5% - 20% among people older than 65 years. The role of Intrinsic Factor in diagnosis Intrinsic Factor has a high affinity and specificity to vitamin B12, which makes it ideal for use in immunoassays. Most commercial assays utilise a competitive binding technique generating a chemiluminescent signal. Commercial assays can usually detect to a level of ~50 pg/ml vitamin B12. Why choose BBI for your supply? BBI is the only commercial manufacturer of high purity Intrinsic Factor. BBI’s porcine Intrinsic Factor is manufactured in the UK, under a quality system compliant with ISO 13485:2016. Using our expertise in raw material sourcing and protein purification we achieve exceptional purity, making BBI the supplier of choice.
IF1

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Attributes

Description

  • Associated Activity
  • IF Content: > 1.00 x106 ng/ml (IF functional ELISA) Purity: > 95% (Size exclusion chromatography SDS-Page: One major band at 55kDa Protein concentration: 0.4 – 0.6 mg protein/ml (Determined by A280 /1.4)
  • Lead Time
  • 6 weeks
  • Storage
  • Store between -25°C and -10°C.
  • Shelf Life
  • 5 years
  • Manufacturer Country
  • UK
  • Source
  • Porcine stomach pyloric section
  • Form
  • IF Content: > 1.00 x106 ng/ml (IF functional ELISA) Purity: > 95% (Size exclusion chromatography SDS-Page: One major band at 55kDa Protein concentration: 0.4 – 0.6 mg protein/ml (Determined by A280 /1.4)

Technical Documents

Product Specification (103.33KB)

Product Information (446.95KB)

Analytical Procedures (303.29KB)

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The acquisition of DIARECT in June 2020 and their world leading recombinant autoimmune antigen capability immediately enhances BBI’s portfolio and position as a ‘complete’ immunoassay reagent supplier. This further enhances BBI’s position as the world’s largest diagnostics components company with a market leading antigen portfolio.

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Maine Biotechnology Services brings 27 years of knowledge, experience, process development, and project management to our customers to ensure the best possible antibodies for any application. As antibody development goals in the biotechnology and pharmaceutical industry have evolved the acquisition of MBS will help BBI further meet and exceed our customers needs.

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