Apo Transferrin

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Apo Transferrin

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#SKU T100-5

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Product Details

Mammalian cell culture in a serum free medium requires an iron transporter such as transferrin. Human transferrin is a 77 kDa beta-glycoprotein with a range of phenotypes based upon the number of sialic acid residues. Each molecule of transferrin specifically binds two Fe3+ molecules. The iron content can be adjusted to give near 100% saturation to yield holo-transferrin (Iron 1200-1600 ug/gm) or depleted to give near zero iron bound to yield apo-transferrin (Iron <50ug/gm protein) or the intermediate- sidero-transferrin (Iron 300-1000ug/gm protein). The secondary role for transferrin in culture media is to bind endogenous metal iron which may cause cell toxicity.

0.1g
T100-5

More information

Attributes

Description

  • Shipping Information
  • Cool Pack
  • Abbreviations
  • Apo Tfn
  • Recommended Use
  • Iron binding and transport in cell culture media
  • Storage
  • 4°C
  • Manufacturer Country
  • UK
  • Presentation Matrix
  • Lyophilised
  • Purity/grade
  • >98%
  • Source
  • plasma

Technical Documents

Certificates Of Analysis (158.36KB)

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