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Hormones

BBI Solutions Hormone Antibodies

BBI Solutions’ monoclonal antibodies for both protein and small molecule human hormones are renowned as sensitive, cost-efficient products for assay developers, manufacturers and researchers worldwide. They are available in both small and bulk quantities depending on your individual needs.   

BBI’s monoclonal antibodies provide sensitive detection of fertility and thyroid hormones such as hCG, Prolactin, Progesterone and TSH with multiple product options. Trust BBI to provide performance proven antibodies to your hormone targets. 

Please contact our Customer Services Team directly to discuss your requirements on tel:+44 (0) 1495 363000 or alternatively you can submit an enquiry here.

 

Antibodies FAQs

Our team are here to help! If you can’t find the answer you are looking for contact us.

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Antibodies are a critical component of the defense arsenal assisting with identifying, capturing, and removing potential threats as well as protecting against future invasions. Antibodies are gammaglobulin proteins, predominantly referred to as immunoglobulins (Ig). A monomeric antibody is composed of two heavy chains and two light chains covalently linked together through disulfide bonds to generate a Y-shaped structure. This Y-shaped structure provides a bifunctional capacity: 1) antigen-binding through the Fab (antigen binding fragment), and 2) interaction with immune cells and
proteins (fragment crystallizable or Fc) to initiate and regulate host defence mechanisms.

Polyclonal antibodies refer to a mixture of immunoglobulin molecules that are secreted against a particular antigen. They interact with different epitopes on the same antigen and their manufacture
does not require the use of hydbridomas. Monoclonal antibodies refer to a homogenous population of antibodies that are produced by a single clone of plasma B cells. They interact with a particular epitope on the antigen and their manufacture requires the use of a hybridoma cell line.

This varies between products, please consult the example Certificate of Analysis for this information.

This varies between products, please consult the example Certificate of Analysis for this information.

Yes, we manufacture many of our own products at our 2 manufacturing sites in Maine, USA and Porton Down, UK. All sites are ISO13485 certified.

BBI Solutions offers a growing portfolio of performance proven antibodies. With our in-house custom antibody expertise, customers can rely on BBI to be a trusted partner in antibody support, from secure
supply, to matched pair recommendations, and trouble shooting performance. Custom manufacturing lots and conjugation services are also value-added services available for most of our antibodies to suit your assay development needs.

A matched antibody pair consists of two antibodies, a capture and a detection antibody. In a matched pair, each antibody is specific for a different and non-interfering epitope of the antigen.

Hybridoma.

Rabbit, Goat and Sheep.

Roller bottle for lot sizes up to 1gram. Hollow fibre continuous perfusion system for lot sizes greater than 1 gram.

4-6 months for a monoclonal antibody and 3-4 months for a polyclonal.

A discussion with a service team member will be necessary regarding this, however monoclonal development projects start at $20k and up.

As this is a complex subject, a separate FAQ has been written for it and can be found here http://www.bbisolutions.com/en/services/monoclonal-development

Why choose BBI’s Solutions Hormone Antibodies? 

BBI Solutions’ monoclonal antibodies for both protein and small molecule human hormones are renowned as sensitive, cost-efficient products for assay developers, manufacturers and researchers worldwide. They are available in both small and bulk quantities depending on your individual needs. 

Fertility Reagents 

  • Matched pair availability for sensitive and specific detection of Prolactin & hCG 
  • Matched pair antibodies as well as recombinant Prolactin antigen are available for a total reagent solution 
  • Performance tested Progesterone antibodies, which recognise Progesterone conjugated at various positions 
  • BBI controlled cell lines and in-house manufacture under cGMP* production and quality management provide increased batch-to-batch consistency 

*21 CFR Part 820, For Research and In Vitro Diagnostic Use Only 

Thyroid Reagents 

  • Matched pairs available 
  • Manufactured onsite for maximum flexibility 
  • BBI controlled cell lines and in-house manufacture under cGMP* production and quality management provide increased batch-to-batch consistency 

 

 

Technical Documents

If you require any further product specific technical information or datasheets please submit your request to our technical team here 

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BBI Solutions Brands

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The acquisition of DIARECT in June 2020 and their world leading recombinant autoimmune antigen capability immediately enhances BBI’s portfolio and position as a ‘complete’ immunoassay reagent supplier. This further enhances BBI’s position as the world’s largest diagnostics components company with a market leading antigen portfolio.

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Maine Biotechnology Services brings 27 years of knowledge, experience, process development, and project management to our customers to ensure the best possible antibodies for any application. As antibody development goals in the biotechnology and pharmaceutical industry have evolved the acquisition of MBS will help BBI further meet and exceed our customers needs.

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Novarum™ technology transforms a smartphone into a diagnostic test reader, empowering users to read and share the results of rapid tests from the point of care. Our pioneering technology can be used by anyone, anywhere, with minimal training: connecting patients and doctors, field workers, lab researchers and primary care clinicians to specialist practices as part of a mobile eco-system.

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