Galectin-3 belongs to the lectin family and is a carbohydrate binding protein. It is predominantly expressed in the colonic and intestinal epithelium. It is also found in the activated macrophages, fibroblasts, tumor cells. The marker is associated with cancer, inflammation and fibrosis, heart disease and stroke. There are various research papers which have suggested different uses of Galectin-3 as a diagnostic marker; a pre-surgical marker for thyroid carcinoma, cell proliferation stimulant, differentiation of benign and malignant thyroid neoplasms, analysis of colorectal cancer progression and Crohns disease. It also has the ability to chemo attract human blood monocytes and macrophages.
More Information
Abbreviation Galectin
Applications Academic, Biosensors, Clinical Chemistry, Control Manufacture, ELISA, Lateral Flow, Life Science
Disease Area Cardiac Markers
Keywords Recombinant Human Galectin-3, Gal-3, Mac-2 antigen, Galactose-specific lectin 3
Molecular Weight 26000 Da
NCBI Entrez Gene ID 3958
Presentation Matrix Single homogenous batch, supplied lyophilised from 0.02M NH4HCO3. May contain traces of buffer salts
Product Category This is an R&D Prototype recombinant antigen
Purity/Grade >96%, defined by Coomassie stained SDS-PAGE
Recommended Use

Galectin -3 is an emerging prognostic biomarker in Heart Failure. Elevated levels are also associated with a variety of cancer types. The recombinant protein can be used as a reagent for creating immunoassay standards and controls.

Shipping Recommendation Below -15°C
Solubility IIt is recommended that PBS is used to reconstitute the material
Source Recombinant from Escherichia Coli
Storage Store -15°C or below
UniProt Number P17931
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