Alpha-1-antitrypsin (A1AT) is a glycoprotein with a molecular weight of 54 kDa and pI of 4.8. It is a serpine protease inhibitor which acts to limit the amount of cell damage and death at the tissue site. Different isoenzymes exist which together form the protease inhibitor system. Phenotype M is the most common and certain variants (S and Z) are associated with alpha-1-antitrypsin deficiency which can lead to emphysema and liver disease.
|Applications||Biosensors, Clinical Chemistry, Control Manufacture, ELISA, Lateral Flow, Life Science|
|Disease Area||Autoimmune Markers|
|Keywords||alpha 1 antitrypsin, A1AT|
|Molecular Weight||54000 Da|
|Product Category||Native Antigens|