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Autoimmune and Inflammation

BBI Solutions Autoimmune and Inflammation Antibodies

At BBI Solutions, we offer a range of monoclonal antibodies to autoimmune and inflammation markers to ensure the reliability and performance of your critical diagnostic assays.   

BBI Solutions’ monoclonal antibodies are renowned as sensitive, cost-efficient products for assay developers, manufacturers and researchers worldwide. They are available in both small and bulk quantities depending on your individual needs.   

Please contact our Customer Services Team directly to disuss your requirements on tel:+44 (0) 1495 363000 or alternatively you can submit an enquiry here.

Inflammation antibodies

Product description Product code Quantity
Ferritin monoclonal antibody BM210-P3A8 1mg
Procalcitonin Monoclonal Antibody BM448-H9F1 1mg
Procalcitonin Monoclonal Antibody BM448-K8C7 1mg
Procalcitonin Monoclonal  Antibody BM448-V4A1 1mg
Rabbit Ferritin Polyclonal Antibody BP230-3 1mg
CRP Recombinant Fab Monoclonal Antibody BR228-D4A3  
Human Lactoferrin Monoclonal Antibody MAB232P 1mg
Human Lactoferrin Monoclonal Antibody MAB233P 1mg
Ferritin Monoclonal Antibody MAB290P 1mg

 

Autoimmune Antibodies (humanised)

Uses of Humanised Antibodies in Immunoassays 

Immunoassays for the detection of antibodies in patient samples and serological methods require reference materials to determine cut-off values and test assay integrity, and these are then included in the kit as calibrators and positive controls. One of the latest advances in assay development is the use of chimeric antibodies as an alternative to characterised disease state plasma which is limited in availability, shows variability and also has safety and ethical issues. BBI has developed a range of specific chimeric antibodies for these applications where disease state plasma is difficult to source. 

Please contact our Customer Services Team directly to discuss your requirements on tel:+44 (0) 1495 363000 or alternatively you can submit an enquiry here.

Disease area Product code Product Quantity
Connective Tissue Diseases PCNA humAb IgG

36600
36601

0.1 mg
1.0 mg
Jo-1 humAb IgG 37300
37301
0.1 mg
1.0 mg
PL-7 humAb IgG 36800
36801
0.1 mg
1.0 mg
PL-12 humAb IgG 36900
36901
0.1 mg
1.0 mg
SRP54 humAb IgG 36500
36501
0.1 mg
1.0 mg
Mi-2 humAb IgG 36700
36701
0.1 mg
1.0 mg
Autoimmune Liver Diseases LKM1 humAb IgG 36400
36401
0.1 mg
1.0 mg
LC1 humAb IgG 37100
37101
0.1 mg
1.0 mg
SLA/LP humAb IgG 36200
36201
0.1 mg
1.0 mg
PDC-E2 humAb IgG 37200
37201
0.1 mg
1.0 mg
Sp100 humAb IgG 37000
37001
0.1 mg
1.0 mg

 

 

 

 

 

FAQs

Our team are here to help! If you can’t find the answer you are looking for contact us.

Antibodies are a critical component of the defense arsenal assisting with identifying, capturing, andremoving potential threats as well as protecting against future invasions. Antibodies are
gammaglobulin proteins, predominantly referred to as immunoglobulins (Ig). A monomeric antibody is composed of two heavy chains and two light chains covalently linked together through disulfide
bonds to generate a Y-shaped structure. This Y-shaped structure provides a bifunctional capacity: 1) antigen-binding through the Fab (antigen binding fragment), and 2) interaction with immune cells and
proteins (fragment crystallizable or Fc) to initiate and regulate host defence mechanisms.

Polyclonal antibodies refer to a mixture of immunoglobulin molecules that are secreted against a particular antigen. They interact with different epitopes on the same antigen and their manufacture
does not require the use of hydbridomas.

Monoclonal antibodies refer to a homogenous population of antibodies that are produced by a single clone of plasma B cells. They interact with a particular epitope on the antigen and their
manufacture requires the use of a hybridoma cell line.

This varies between products, please consult the example Certificate of Analysis for this information.

This varies between products, please consult the example Certificate of Analysis for this information.

Yes, we manufacture many of our own products at our 2 manufacturing sites in Maine, USA and Porton Down, UK. All sites are ISO13485 certified.

BBI Solutions offers a growing portfolio of performance proven antibodies. With our in-house custom antibody expertise, customers can rely on BBI to be a trusted partner in antibody support, from secure
supply, to matched pair recommendations, and trouble shooting performance. Custom manufacturing lots and conjugation services are also value-added services available for most of our antibodies to suit your assay development needs.

A matched antibody pair consists of two antibodies, a capture and a detection antibody. In a matched pair, each antibody is specific for a different and non-interfering epitope of the antigen.

Hybridoma.

Rabbit, Goat and Sheep.

Roller bottle for lot sizes up to 1gram. Hollow fibre continuous perfusion system for lot sizes greater than 1 gram.

4-6 months for a monoclonal antibody and 3-4 months for a polyclonal.

A discussion with a service team member will be necessary regarding this, however monoclonal development projects start at $20k and up.

High performing Autoimmune and Inflammation Antibodies

At BBI Solutions, we offer a range of monoclonal antibodies to a variety of inflammation markers to ensure the reliability and performance of your critical diagnostic assays.   

BBI Solutions’ monoclonal antibodies are renowned as sensitive, cost-efficient products for assay developers, manufacturers and researchers worldwide. They are available in both small and bulk quantities depending on your individual needs.   

CRP 

  • Monoclonal antibody for sensitive detection 
  • Multiple applications tested 
  • Total reagent solution with BBI’s own CRP antigen 

Procalcitonin 

  • Multiple matched pair options 
  • Excellent sensitivity 
  • Competitive bulk pricing 
  • Total reagent solution with BBI’s own Procalcitonin antigen 

Ferritin 

  • Multiple matched pair options including self-pair 
  • Sensitive detection of ferritin 
  • Total reagent solution with BBI’s own Ferritin antigen 

 

 

 

Technical Documents

If you require any further product specific technical information or datasheets please submit your request to our technical team here 

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